The PAP IMI operating principle and mechanism of action
The PAPIMI device produces pulsed electromagnetic type ELF 
(Extremely Low Frequency), also known as waves PEMF (Pulsed Electro 
Magnetic Field). These waves, given their very short 
duration (40-50 microseconds) do not heat the tissue and are able to 
cross biological tissue up to 15 to 20 inches deep, thus favoring the 
stimulation and regeneration because they act directly on the physiology
 the cell.
The pulse is produced in a Plasma ROOM, located inside a solenoidal probe in concentric coils. The probe consists of a silicone tube containing air is circulated in which an electric current that turns the air into plasma. The
 way that gets the electromagnetic pulse makes it 100% biocompatible, 
because it is rich of typical frequencies of the constituent elements of
 air and the necessities of life, such as oxygen and nitrogen.
Figure 1 Membrane potential
The PAPIMI device is used to reactivate the cell physiology in all 
pathologies osteo-articular muscle and nerve, and also eliminates the 
pain.
The pain is usually
 caused by trauma, injuries and accidents of various kinds that 
determine tissue degeneration, inflammation and, therefore, pain. The
 multiplicity of agents damaging the body responds with a unique defense
 mechanism, inflammation, and repair the injured tissue activates 
mechanisms more or less specific. At the cellular level, 
the inflammatory state leads to a lowering of the membrane potential 
which, in turn, causes a reduction of the normal activity of the cell 
involved, and a reduction of its metabolism.
Reduces the normal transfer 
of nutrients from outside, through the specific mechanisms of exchange, 
which, first of all, the sodium potassium pump, and reduces the 
elimination of waste substances toxic to the cell. Gradually,
 the cell becomes depleted of oxygen, is enriched with toxins, and so is
 less than the production of ATP (adenine triphosphate).
Figure 2
 The diagram shows the relationship between the concentration inside the
 cell Na + ions and the potential trans-membrane associated, since they 
are related to the health status of the cell. The device Papimi ® increases the TMP (Trans Membrane Potential) and decreases Natremia (concentration of Na-).
All cellular 
functions depend on the continued availability of energy derived from 
catabolism of organic molecules during the process of cellular 
respiration, the energy released is stored in the form of molecules of 
ATP (adenosine triphosphate). ATP is the energy reserves, readily available for all metabolic functions of the cell.
The electromagnetic field 
generated by the device PAP IMI device is to act 
directly at the cellular level, exploiting the natural ability of 
biological structures interact with electromagnetic fields. It
 is essentially to create resonances, as is now known, each substance 
has its own characteristic electromagnetic spectrum, and any substance 
interacts with electromagnetic waves is so non-specific (for example 
through the transfer of energy) and specifically (interactions based on 
the particular resonance frequency range).
Figure 3
 The diagram shows the relationship between the concentration of 
intracellular K + and Na + ions, since they are connected to the 
trans-membrane potential and health status of the cells. The
 device Papimi ® pushes the curve from the area in the lower right to 
upper left area, where he represented the condition of young and healthy
 cells.
The membrane potential has a close relationship with the state of health of the cells. Under
 physiological conditions this potential assumes a certain value which, 
depending on the type of cell is between -70 and -90 mV. This potential must be kept constant because the cell remains in physiology.
So happens that, for 
certain frequencies, the wave emitted by the device is able to interact,
 resonating with the electromagnetic field produced by the cell. In addition, the cell membrane, by its very nature, conveys well the electromagnetic field.
The effect of 
electromagnetic pulse has features that allow you to restore the 
membrane potential, altered by the pathological state. Moreover,
 precisely due to its composition, the wave penetrates into the cell by 
stimulating mitochondrial activity, cellular respiration and ATP 
production.
Therefore, at the cellular 
level, it has a dual effect: stimulation of bio-electric nature, because
 it restores the normal membrane potential was altered by the disease, 
and stimulation of natural bio-chemistry, because the impulse is able to
 penetrate inside the cell, which is to restore the physiology.
 
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